The project to construct four nuclear reactors has repeatedly run into delays, including being briefly halted after Turkey downed a Russian jet near the Syrian border in November 2015. Ties have since normalized between the two countries and work on the plant has resumed.
It is now expected to be completed by 2023 and should meet 6-7 percent of Turkey's electricity demand once it is fully operational, energy regulator EPDK said in a statement.
Rosatom has sold several nuclear reactors to developing countries under a model by which Russia finances, builds and operates the nuclear plant and sells power to its customer.
EPDK said it had given Rosatom's project company Akkuyu Nukleer AS a 49-year production license.
Dependent on imports for almost all of its energy, Turkey has embarked on an ambitious nuclear program, commissioning Rosatom in 2013 to build the four 1,200 megawatt (MW) reactors.
With Turkey's energy imports costing about $50 billion annually, Ankara wants at least 5 percent of its electricity generation to come from nuclear energy in under a decade, cutting dependency on natural gas largely bought from Russia.
Rosatom initially pledged to have the first of the four reactors in Akkuyu ready by 2019 before it suffered delays.